Comparison of TLR2/1, NF-кB p105/50, NF-кB p65, and TNF-α expressions in the macrophages between multibacillary leprosy patients with and without erythema nodosum leprosum signifying innate immune system activity
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چکیده
منابع مشابه
Expressions of IL-6, TNF-α and NF-кB in the skin of Chinese brown frog (Rana dybowskii)
The cytokine interleukin-6 (IL-6) mediates a wide range of inflammatory and immune responses. Tumor Necrosis Factor α (TNF-α) has a myriad of pro-inflammatory effects on the skin. Nuclear factor κB (NF-κB) is a transcriptional factor that regulates a battery of genes that are critical to immune system. In this study, we investigated the localizations and expression levels of IL-6, TNF-α and NF-...
متن کاملDysregulation of IL-4 expression in lepromatous leprosy patients with and without erythema nodosum leprosum.
In order to increase our understanding of the immunological basis of erythema nodosum leprosum (ENL), we studied Th-like cytokine profiles in 130 leprosy patients, employing both the conventional and a novel, real-time, fluorogenic reverse transcriptase-based PCR (RT-PCR). The concomitant expression of both Th-like cytokines, interferon-gamma and IL-4, and the regulatory cytokines, IL-10 and IL...
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ژورنال
عنوان ژورنال: Bali Medical Journal
سال: 2019
ISSN: 2302-2914,2089-1180
DOI: 10.15562/bmj.v8i1.1482